Foldit
Free
Foldit is an innovative platform that allows you to contribute to scientific research by solving puzzles related to protein folding. This helps scientists understand diseases and develop cures.

Our take
Turn gaming into scientific discovery.
So, Foldit is this pretty neat puzzle game that’s all about folding proteins. Sounds weird, right? But it’s actually kinda fascinating. You’re basically playing with these complex shapes, trying to get them into the right form. It’s like Tetris, but with more biology involved. What’s cool is that while you’re playing, you’re also contributing to scientific research. That’s a win-win if you ask me, especially if you’re into science and gaming.
Here’s the thing, though: it’s not the easiest game to just jump into. You might feel a bit lost at first if you don’t have some background in biology or chemistry. The tutorials try to help, but they can be a little dense. If you’re patient and curious, though, it’s totally worth sticking with it. Once you get the hang of it, there’s this satisfying “aha” moment when you finally get a protein folded just right. That makes it all worthwhile.
On the downside, the graphics are nothing to write home about. It’s not winning any beauty contests, that’s for sure. But I guess that’s not the main focus here. It’s more about the brain work and less about eye candy. Still, a bit of polish in the visuals wouldn’t hurt. It feels a little clunky and dated, which might put off some folks who are used to more modern-looking games.
Another thing to keep in mind is that this game is really a niche thing. If you’re not into puzzles or science, Foldit might feel more like work than play. It doesn’t have the same kind of instant gratification you get from other games. It’s more of a slow burn, a “sit down with a cup of coffee and figure it out” kind of deal. But if you’re into solving tough problems, it can be incredibly rewarding.
Overall, Foldit is a unique blend of gaming and science that you don’t see every day. It’s a bit rough around the edges, but the concept is solid. If you’re looking for something different and don’t mind a bit of a learning curve, give it a shot. Just know that it’s not your typical game night pick — it’s more like a brain workout. But hey, sometimes that’s exactly what you need to shake things up.